Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1338816 | 1.00 | MCHR1 (0.37) | MCHR1CYP3A4CYP2C19OPRL1NPY1R | |
| SCHEMBL3260114 | 0.93 | ALPL (0.36) | MCHR1CYP3A4CYP2C19KCNH2CHRNA7 | |
| Hydrochloric Acid SCHEMBL1339640 | 0.93 | ALPL (0.36) | MCHR1CYP3A4CYP2C19KCNH2CHRNA7 | |
| SCHEMBL3140076 | 0.92 | MOK (0.38) | KCNH2CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL1340198 | 0.92 | MOK (0.38) | KCNH2CNR1CNR2 | |
| SCHEMBL4762585 | 0.88 | DCTPP1 (0.36) | MCHR1NPY1RCNR1CNR2SIGMAR1 | |
| SCHEMBL1338233 | 0.87 | GABRA1 (0.37) | OPRL1KCNH2CNR1CNR2SIGMAR1 | |
| SCHEMBL1339358 | 0.86 | CNR1 (0.38) | OPRL1CNR1CNR2SIGMAR1 | |
| SCHEMBL1337046 | 0.84 | GABRG2 (0.42) | KCNH2CNR1CNR2 | |
| SCHEMBL1339487 | 0.82 | MCHR1 (0.41) | MCHR1CYP3A4CYP2C19OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940840-B1 | 6-HETEROARYLPYRIDOINDOLONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-07-21 | — | — | EP | disclosed |