Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139962 | 0.88 | MCHR1 (0.37) | CNR1CNR2MCHR1SIGMAR1NPY1R | |
| Hydrochloric Acid SCHEMBL1338816 | 0.88 | MCHR1 (0.37) | CNR1CNR2MCHR1SIGMAR1NPY1R | |
| SCHEMBL3260114 | 0.81 | ALPL (0.36) | MCHR1ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL3140076 | 0.80 | MOK (0.38) | CNR1CNR2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1338233 | 0.74 | GABRA1 (0.37) | CNR1CNR2ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL1339358 | 0.73 | CNR1 (0.38) | CNR1CNR2ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL1337046 | 0.71 | GABRG2 (0.42) | CNR1CNR2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3140152 | 0.70 | HTT (0.38) | CNR2ALDH1A1KDM4EPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL1339128 | 0.70 | HTT (0.38) | CNR2ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL1339487 | 0.70 | MCHR1 (0.41) | MCHR1ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940840-A1 | 6-HETEROARYLPYRIDOINDOLONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045758-A1 | 6-HETEROARYLPYRIDOINDOLONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2007-04-26 | — | — | WO | disclosed |