SCHEMBL3140737

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3141897	0.86	AGBL2 (0.34)	CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2
	SCHEMBL5356876	0.83	CYP3A4 (0.35)	CYP3A4ACHESMN1; SMN2AGBL2RXRA
	SCHEMBL18896446	0.83	CYP3A4 (0.44)	CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2
	SCHEMBL422352	0.83	RXRA (0.51)	CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2
	SCHEMBL15957693	0.82	CYP3A4 (0.42)	CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4060815	0.82	POLB (0.43)	CYP3A4ALDH1A1KDM4EL3MBTL1AGBL2
	SCHEMBL3138059	0.79	CYP3A4 (0.49)	CYP3A4ACHEALDH1A1KDM4EMAPT
	SCHEMBL3142173	0.79	PTPN1 (0.35)	KDM4EL3MBTL1AGBL2DHODHGLRA3
	SCHEMBL28114010	0.79	CYP3A4 (0.41)	CYP3A4ALDH1A1MAPK1SMN1; SMN2KDM4E
	SCHEMBL4642911	0.78	CYP3A4 (0.50)	CYP3A4ACHEALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.