Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411613 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNACYP2C9 | |
| SCHEMBL31411660 | 0.72 | LMNA (0.52) | ALDH1A1MAPTSMN1; SMN2LMNACYP2C9 | |
| SCHEMBL31411636 | 0.71 | ALOX15 (0.42) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL31411690 | 0.68 | SMN1; SMN2 (0.55) | ALDH1A1MAPTSMN1; SMN2LMNACYP2C9 | |
| SCHEMBL31411600 | 0.68 | HPGD (0.61) | ALDH1A1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31411772 | 0.66 | LMNA (0.60) | ALDH1A1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31411783 | 0.65 | ALDH1A1 (0.57) | ALDH1A1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31411776 | 0.65 | CRHR1 (0.37) | KMT2AMAPTLMNAMEN1CYP2C9 | |
| SCHEMBL31411771 | 0.64 | ALDH1A1 (0.39) | ALDH1A1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31411699 | 0.62 | POLB (0.65) | ALDH1A1MAPTSMN1; SMN2LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |