Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423108 | 0.80 | SMYD3 (0.42) | TSHRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31423010 | 0.77 | CAMKK2 (0.43) | NPC1RAB9AKDM4E | |
| SCHEMBL31422972 | 0.77 | CAMKK2 (0.43) | NPC1RAB9AKDM4E | |
| SCHEMBL31422933 | 0.76 | KDM4E (0.47) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL31423247 | 0.76 | CNR2 (0.40) | KDM5AKDM5BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31423086 | 0.75 | CNR2 (0.39) | KDM5AKDM5BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31423039 | 0.74 | CAMKK2 (0.44) | KDM4E | |
| SCHEMBL31423292 | 0.74 | CAMKK1 (0.36) | ALDH1A1 | |
| SCHEMBL31422800 | 0.74 | CNR2 (0.36) | KDM5AKDM5BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31422779 | 0.74 | CNR2 (0.42) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |