Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479161 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL27096449 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL31273396 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL31229604 | 0.88 | MAOB (0.46) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL31423294 | 0.85 | TBK1 (0.45) | KDM4EALDH1A1GAASMYD3IKBKE | |
| SCHEMBL25396475 | 0.84 | MMP9 (0.43) | TLR9TLR8POLBRAB9ASMN1; SMN2 | |
| SCHEMBL31273371 | 0.77 | DAO (0.37) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL31423089 | 0.77 | MAOB (0.51) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL31422768 | 0.76 | MAOB (0.53) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL31273139 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10GAASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |