Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273139 | 0.91 | KDM4E (0.46) | TBK1IKBKEKDM4EALDH1A1POLB | |
| SCHEMBL31423285 | 0.88 | ACMSD (0.52) | TBK1IKBKEKDM4EALDH1A1POLB | |
| SCHEMBL31273616 | 0.88 | ACMSD (0.49) | TBK1IKBKEKDM4EALDH1A1POLB | |
| SCHEMBL31423183 | 0.87 | ACMSD (0.54) | TBK1IKBKESERPINE1KDM4EALDH1A1 | |
| SCHEMBL31423110 | 0.85 | KDM4E (0.40) | TBK1IKBKEPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL31229604 | 0.83 | MAOB (0.46) | TBK1KDM4EALDH1A1POLBGAA | |
| SCHEMBL31423104 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1POLBGAAMAOB | |
| SCHEMBL27096449 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1POLBGAAMMP9 | |
| SCHEMBL29479161 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1POLBGAAMMP9 | |
| SCHEMBL25396475 | 0.73 | MMP9 (0.43) | POLBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |