Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273616 | 0.94 | ACMSD (0.49) | KDM4EALDH1A1GAAPOLBACMSD | |
| SCHEMBL31423285 | 0.94 | ACMSD (0.52) | KDM4EALDH1A1GAAPOLBACMSD | |
| SCHEMBL31423183 | 0.93 | ACMSD (0.54) | KDM4EALDH1A1GAAPOLBACMSD | |
| SCHEMBL31423294 | 0.91 | TBK1 (0.45) | KDM4EALDH1A1GAAPOLBACMSD | |
| SCHEMBL29479161 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1GAAPOLBMMP9 | |
| SCHEMBL27096449 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1GAAPOLBMMP9 | |
| SCHEMBL31423104 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1GAAPOLBMAOB | |
| SCHEMBL20494813 | 0.80 | HSD17B10 (0.53) | KDM4EALDH1A1ACMSDMMP9HPGD | |
| SCHEMBL2807085 | 0.76 | CASP3 (0.55) | KDM4EALDH1A1GAAPOLBHPGD | |
| SCHEMBL29415463 | 0.76 | CASP3 (0.55) | KDM4EALDH1A1GAAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| CN-119101045-A | Nitrogen-containing heterocyclic compounds, and preparation method and application thereof | 上海宇道生物技术有限公司 | 2024-12-10 | — | — | CN | disclosed |