Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535203 | 0.84 | DHFR (0.31) | NR1H2NR1H3AGBL2DHFRALDH1A1 | |
| SCHEMBL10233515 | 0.83 | GPBAR1 (0.39) | NR1H2NR1H3AGBL2ALDH1A1MBOAT4 | |
| SCHEMBL31435358 | 0.81 | AGBL2 (0.33) | NR1H2NR1H3AGBL2ALDH1A1MBOAT4 | |
| SCHEMBL31435301 | 0.78 | MBOAT4 (0.42) | NOTUMS1PR1ALDH1A1MBOAT4ASPH | |
| SCHEMBL19609733 | 0.78 | NOTUM (0.46) | NOTUMS1PR1DHFRALDH1A1 | |
| SCHEMBL15417759 | 0.76 | NOS3 (0.44) | NOTUMDHFRALDH1A1ABL1 | |
| SCHEMBL6921026 | 0.76 | UHRF1 (0.43) | NR1H2NR1H3AGBL2NOTUMS1PR1 | |
| SCHEMBL24081712 | 0.75 | GABRA2 (0.39) | NR1H2NR1H3S1PR1ALDH1A1AR | |
| SCHEMBL20802304 | 0.75 | AGBL2 (0.35) | NR1H2NR1H3AGBL2NOTUMS1PR1 | |
| SCHEMBL15350441 | 0.73 | ALDH1A1 (0.40) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090792-A1 | AMIDE PRODRUGS AND USES THEREOF | AUTOBAHN THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |