Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141259 | 0.87 | KMT2A (0.47) | MRGPRX4KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL8207859 | 0.86 | MRGPRX4 (0.55) | MRGPRX4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11350918 | 0.85 | MRGPRX4 (0.55) | MRGPRX4KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL767466 | 0.83 | SENP1 (0.50) | MRGPRX4KMT2ARAB9AMEN1MAPT | |
| SCHEMBL17301243 | 0.80 | MAPT (0.50) | KMT2AMEN1MAPTTDP1 | |
| SCHEMBL17826638 | 0.80 | SENP1 (0.46) | KMT2ANPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL28703403 | 0.79 | HPGD (0.47) | MRGPRX4KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL3149726 | 0.79 | PTK2B (0.51) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL31572520 | 0.77 | TDP1 (0.56) | MRGPRX4KMT2AMEN1SMN1; SMN2TTR | |
| SCHEMBL618918 | 0.77 | TDP1 (0.56) | MRGPRX4KMT2AMEN1SMN1; SMN2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041860-A1 | POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME | UBE INDUSTRIES, LTD. (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041860-A1 | POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME | DDC, AOC1, DDT | MRGPRX4 3753/4885KMT2A 334/4885NPC1 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.