SCHEMBL3145237

SCHEMBL3145237

Cc1ccc(N2C=NC(S)N2Cc2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RGS4 P49798 1/20 0.41
▸ RGS8 P57771 1/20 0.41
▸ LMNA P02545 3/20 0.41
▸ POLB P06746 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ CYP19A1 P11511 1/20 0.36
▸ HPGD P15428 2/20 0.35
▸ GAA P10253 2/20 0.35
▸ MAPT P10636 4/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ TP53 P04637 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ BACE1 P56817 1/20 0.35
▸ NPC1 O15118 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3137528 0.85 RGS4 (0.45) RGS4RGS8LMNAALDH1A1CYP19A1
SCHEMBL3133254 0.80 RGS4 (0.35) RGS4RGS8ALDH1A1HPGDMAPT
SCHEMBL3145221 0.68 POLB (0.46) RGS4RGS8LMNAPOLBALDH1A1
SCHEMBL3150312 0.61 KMT2A (0.38) LMNAALDH1A1MAPK1MAPTNPSR1
SCHEMBL12385909 0.60 DRD4 (0.77) LMNAPOLBALDH1A1MAPK1HPGD
SCHEMBL13381620 0.59 LMNA (1.00) LMNAPOLBALDH1A1MAPK1GAA
SCHEMBL1044086 0.59 LMNA (0.55) RGS4RGS8LMNAPOLBALDH1A1
SCHEMBL3012641 0.59 ALDH1A1 (0.60) LMNAPOLBALDH1A1CYP19A1HPGD
P-Xylene SCHEMBL11045590 0.58 LMNA (0.54) RGS4RGS8LMNAPOLBALDH1A1
SCHEMBL15202275 0.58 ACHE (0.47) LMNAPOLBCYP19A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 — — EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 — — US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 — — US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
US-20090246699-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 — — EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 — — US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 — — US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 — — EP disclosed
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