SCHEMBL3133254

SCHEMBL3133254

SC1N=CN(c2cc(Cl)cc(Cl)c2)N1Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RGS4 P49798 2/20 0.35
▸ RGS8 P57771 2/20 0.35
▸ CXCR2 P25025 1/20 0.35
▸ SPR P35270 3/20 0.34
▸ NPSR1 Q6W5P4 2/20 0.33
▸ PKM P14618 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HTT P42858 2/20 0.33
▸ ITGB2 P05107 1/20 0.33
▸ ICAM1 P05362 1/20 0.33
▸ ITGAL P20701 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ KDM4A O75164 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ SIGMAR1 Q99720 2/20 0.33
▸ SMO Q99835 2/20 0.32
▸ CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3145237 0.80 RGS4 (0.41) RGS4RGS8NPSR1ALDH1A1HTT
SCHEMBL3137528 0.77 RGS4 (0.45) RGS4RGS8CXCR2NPSR1ALDH1A1
SCHEMBL3839861 0.64 SIGMAR1 (0.51) RGS4RGS8ALDH1A1HTTKDM4E
SCHEMBL6766331 0.58 DPP4 (0.48) ALDH1A1ITGB2ICAM1ITGALHSD17B10
SCHEMBL16770503 0.57 CALM1 (0.60) ALDH1A1HPGDTSHRHSD17B10SIGMAR1
Hydrogen Sulfide SCHEMBL28232332 0.55 CALM1 (0.57) ALDH1A1HPGDTSHRHSD17B10SIGMAR1
SCHEMBL15202275 0.54 ACHE (0.47) SIGMAR1MAPTF2PLGELANE
SCHEMBL8744607 0.53 GSK3A (0.31) —
SCHEMBL1515715 0.53 L3MBTL1 (0.70) KDM4EL3MBTL1SIGMAR1MAPT
SCHEMBL23487472 0.53 MAOA (0.46) ALDH1A1HPGDHSD17B10SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 — — EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 — — US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 — — US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
US-20090246699-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 — — EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 — — US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 — — US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 — — EP disclosed
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