SCHEMBL3145221

SCHEMBL3145221

Cc1ccc(N2CNC(S)N2Cc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.46
▸ LMNA P02545 2/20 0.46
▸ ACHE P22303 3/20 0.42
▸ BACE1 P56817 3/20 0.42
▸ BCHE P06276 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ RGS4 P49798 1/20 0.37
▸ RGS8 P57771 1/20 0.37
▸ PKM P14618 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ TAAR1 Q96RJ0 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ HRH1 P35367 1/20 0.36
▸ DRD2 P14416 1/20 0.36
▸ DRD4 P21917 1/20 0.36
▸ DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3146287 0.90 DRD4 (0.41) ACHEBACE1BCHEALDH1A1KMT2A
SCHEMBL3137509 0.85 SIGMAR1 (0.50) LMNAACHEBACE1ALDH1A1RGS4
SCHEMBL3146092 0.83 BCHE (0.45) POLBLMNAACHEBACE1BCHE
SCHEMBL3133246 0.81 SIGMAR1 (0.38) LMNAMAPTNPSR1ALDH1A1MAPK1
SCHEMBL3141469 0.77 MAPK1 (0.36) POLBLMNAACHEBACE1BCHE
SCHEMBL3840283 0.75 HTR1A (0.44) ACHEMAPTDRD2
SCHEMBL3144726 0.71 DRD2 (0.37) SMN1; SMN2DRD2DRD3
SCHEMBL3145237 0.68 RGS4 (0.41) POLBLMNAACHEBACE1MAPT
SCHEMBL3146314 0.67 SIGMAR1 (0.34) POLBMAPK1SMN1; SMN2MEN1KMT2A
SCHEMBL3836590 0.65 SLC6A3 (0.41) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 — — EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 — — US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 — — US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
US-20090246699-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 — — EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 — — US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 — — US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 — — EP disclosed
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