Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337579 | 0.87 | MEN1 (0.40) | ENPP2NOS3NOS1NOS2 | |
| SCHEMBL123838 | 0.87 | TSHR (0.61) | ENPP2NOS3NOS1NOS2TSHR | |
| Hydrochloric Acid SCHEMBL14334287 | 0.84 | ENPP2 (0.58) | ENPP2NOS3NOS1NOS2TSHR | |
| SCHEMBL9999688 | 0.79 | ENPP2 (0.54) | ENPP2NOS3NOS1NOS2TSHR | |
| SCHEMBL3267429 | 0.78 | ACHE (0.48) | ENPP2NOS3NOS1NOS2TSHR | |
| SCHEMBL1023596 | 0.75 | ENPP2 (0.50) | ENPP2NOS3NOS1NOS2TSHR | |
| SCHEMBL5981892 | 0.75 | ENPP2 (0.50) | ENPP2NOS3NOS1NOS2TSHR | |
| SCHEMBL2642411 | 0.75 | PRSS1 (0.52) | ENPP2NOS3NOS1NOS2TSHR | |
| SCHEMBL6073283 | 0.75 | FOLH1 (0.52) | ENPP2NOS3NOS1NOS2TSHR | |
| SCHEMBL7713859 | 0.75 | ENPP2 (0.50) | ENPP2NOS3NOS1NOS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555257-B1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |
| US-7342138-B2 | Process for producing aromatic aldehyde | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-7262316-B2 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20070004934-A1 | Process for producing aromatic aldehyde | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1661877-A1 | PROCESS FOR PRODUCING AROMATIC ALDEHYDE | Ihara Chemical Industry Co., Ltd. (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20060069282-A1 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| EP-1555257-A1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069282-A1 | Process for producing aromatic nitrile compound | ODC1, ALKBH3, GNMT | ENPP2 4589/4885NOS3 19/4885NOS1 14/4885 |
| US-20070004934-A1 | Process for producing aromatic aldehyde | ALKBH3, AOX1, ALDH3A1 | ENPP2 4641/4885NOS3 634/4885NOS1 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.