Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 11/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455407 | 0.87 | GSK3B (0.35) | ALDH1A1TDP1PDCD1LG2CD274 | |
| SCHEMBL31455206 | 0.78 | CHRM2 (0.38) | HDAC2HDAC1HDAC3PIK3CAPIM1 | |
| SCHEMBL31455186 | 0.73 | AKT1 (0.57) | — | |
| SCHEMBL31455366 | 0.72 | ALDH1A1 (0.61) | HDAC2HDAC1ALDH1A1TDP1 | |
| SCHEMBL31454994 | 0.72 | TNIK (0.36) | HDAC2HDAC1ALDH1A1 | |
| SCHEMBL31455120 | 0.71 | PDE5A (0.43) | HDAC2PIK3CAALDH1A1 | |
| SCHEMBL31455090 | 0.71 | LTA4H (0.47) | ALDH1A1CHRM2SYK | |
| SCHEMBL31455623 | 0.69 | ALDH1A1 (0.53) | HDAC2HDAC1ALDH1A1TDP1 | |
| SCHEMBL31455390 | 0.69 | HDAC2 (0.56) | HDAC2HDAC1 | |
| SCHEMBL25385310 | 0.67 | ABCG2 (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |