Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455146 | 0.88 | GSK3A (0.35) | CHRM2CHRM1CHRM3PRKAA2SYK | |
| SCHEMBL31455116 | 0.78 | HDAC2 (0.35) | CHRM2CHRM1CHRM3PIM1PIM3 | |
| SCHEMBL31455391 | 0.74 | AKT1 (0.55) | — | |
| SCHEMBL31455311 | 0.73 | DRD2 (0.46) | SYKJAK2 | |
| SCHEMBL31455244 | 0.72 | CYP2C9 (0.43) | SYKMCHR1JAK2 | |
| SCHEMBL31455120 | 0.71 | PDE5A (0.43) | HDAC2PIK3CAJAK2JAK1 | |
| SCHEMBL31455090 | 0.68 | LTA4H (0.47) | CHRM2SYKJAK2 | |
| SCHEMBL31455195 | 0.68 | HDAC1 (0.45) | HDAC1HDAC2SYKPIK3CADYRK1A | |
| SCHEMBL31455366 | 0.68 | ALDH1A1 (0.61) | HDAC1HDAC2 | |
| SCHEMBL25385310 | 0.66 | ABCG2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |