Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.35 |
| ▸ | GSK3A | P49840 | 5/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455116 | 0.87 | HDAC2 (0.35) | ALDH1A1TDP1PDCD1LG2CD274 | |
| SCHEMBL31455146 | 0.79 | GSK3A (0.35) | GSK3BGSK3AAURKAMEN1CYP2C19 | |
| SCHEMBL31455013 | 0.76 | GSK3B (0.44) | GSK3BGSK3AAURKAPIN1MAPT | |
| SCHEMBL31455394 | 0.74 | MAPT (0.36) | GSK3BGSK3AAURKAMAPTALDH1A1 | |
| SCHEMBL31455141 | 0.74 | POLB (0.36) | MAPTMAPK1NPC1RAB9AMEN1 | |
| SCHEMBL31455247 | 0.74 | PIN1 (0.46) | GSK3BGSK3AAURKAPIN1MAPT | |
| SCHEMBL31455342 | 0.74 | ALDH1A1 (0.57) | MAPTMEN1KMT2ABRD4ALDH1A1 | |
| SCHEMBL31455412 | 0.73 | GSK3B (0.43) | GSK3BGSK3AAURKAPIN1MAPT | |
| SCHEMBL31455591 | 0.72 | GSK3B (0.39) | GSK3BGSK3AAURKAPIN1MAPT | |
| SCHEMBL25384573 | 0.69 | ABCG2 (0.54) | GSK3BGSK3AAURKAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |