Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455425 | 0.86 | GSK3B (0.36) | LTA4HMCHR1ALDH1A1MAPTHPGD | |
| SCHEMBL31420369 | 0.83 | NAAA (0.40) | L3MBTL1CYP2D6CYP2C19MCHR1ALDH1A1 | |
| SCHEMBL31455090 | 0.77 | LTA4H (0.47) | LTA4HALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL31455366 | 0.77 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL25928005 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL8949097 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL31455623 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDHSD17B10TDP1 | |
| SCHEMBL31455034 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL25385310 | 0.72 | ABCG2 (0.61) | L3MBTL1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL31455169 | 0.72 | ABCG2 (0.61) | L3MBTL1ALDH1A1MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |