Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | VCP | P55072 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455172 | 0.86 | LTA4H (0.36) | GSK3BGSK3ACPB1LTA4HVCP | |
| SCHEMBL31420344 | 0.85 | NAAA (0.37) | GSK3BGSK3AAURKATYMSMAPT | |
| SCHEMBL31455312 | 0.79 | LTA4H (0.45) | LTA4H | |
| SCHEMBL31455342 | 0.79 | ALDH1A1 (0.57) | MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL31455394 | 0.78 | MAPT (0.36) | GSK3BGSK3AAURKATYMSMAPT | |
| SCHEMBL31455064 | 0.75 | GSK3B (0.45) | GSK3BGSK3AAURKATYMSMAPT | |
| SCHEMBL31455469 | 0.74 | MAPT (0.43) | MAPTNPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL25928005 | 0.74 | ALDH1A1 (0.50) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8949097 | 0.74 | ALDH1A1 (0.50) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL25384573 | 0.74 | ABCG2 (0.54) | GSK3BGSK3AAURKAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |