Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 7/20 | 0.36 |
| ▸ | JAK3 | P52333 | 6/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420326 | 0.87 | NAMPT (0.40) | PRKCQABCG2USP30JAK2JAK3 | |
| SCHEMBL31455264 | 0.85 | USP30 (0.39) | PRKCQUSP30JAK2JAK3 | |
| SCHEMBL31455102 | 0.82 | NAMPT (0.45) | PRKCQUSP30JAK2JAK3PTK2 | |
| SCHEMBL31455683 | 0.82 | JAK2 (0.46) | JAK2JAK3PTK2JAK1 | |
| SCHEMBL31455378 | 0.82 | HPGDS (0.44) | PRKCQUSP30JAK2JAK3PTK2 | |
| SCHEMBL31420375 | 0.80 | NAMPT (0.51) | JAK2JAK3PTK2JAK1 | |
| SCHEMBL31455277 | 0.80 | PRKCQ (0.37) | PRKCQUSP30TP53BACE1 | |
| SCHEMBL31455545 | 0.79 | ABCG2 (0.41) | ABCG2BRD4 | |
| SCHEMBL31455653 | 0.77 | ABCG2 (0.39) | ABCG2BRD4JAK2JAK1 | |
| SCHEMBL30802461 | 0.76 | JAK2 (0.44) | JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |