Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420326 | 0.88 | NAMPT (0.40) | PRKCQUSP30RORCHPGDSGPR119 | |
| SCHEMBL31455102 | 0.81 | NAMPT (0.45) | PRKCQUSP30HPGDSGPR119TP53 | |
| SCHEMBL31455378 | 0.81 | HPGDS (0.44) | PRKCQUSP30HPGDSGPR119NAMPT | |
| SCHEMBL31455264 | 0.80 | USP30 (0.39) | PRKCQUSP30HPGDSGPR119 | |
| SCHEMBL31455205 | 0.80 | PRKCQ (0.38) | PRKCQUSP30BACE1TP53 | |
| SCHEMBL31420375 | 0.79 | NAMPT (0.51) | GPR119NAMPT | |
| SCHEMBL31455683 | 0.79 | JAK2 (0.46) | SLC34A1 | |
| SCHEMBL31455107 | 0.79 | BRD9 (0.41) | GAAMAPT | |
| SCHEMBL31455299 | 0.79 | SLC34A1 (0.40) | PRKCQUSP30SLC34A1RORCTP53 | |
| SCHEMBL31455485 | 0.78 | ALDH1A1 (0.44) | USP30RORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |