Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 12/20 | 0.46 |
| ▸ | JAK3 | P52333 | 5/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.46 |
| ▸ | JAK1 | P23458 | 8/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420326 | 0.91 | NAMPT (0.40) | JAK2JAK3PTK2LCKBTK | |
| SCHEMBL31455102 | 0.85 | NAMPT (0.45) | JAK2JAK3PTK2JAK1LCK | |
| SCHEMBL31455378 | 0.84 | HPGDS (0.44) | JAK2JAK3PTK2JAK1LCK | |
| SCHEMBL31455504 | 0.84 | MKNK1 (0.40) | JAK2JAK3PTK2PTPN2PTPN1 | |
| SCHEMBL31420375 | 0.83 | NAMPT (0.51) | JAK2JAK3PTK2JAK1PTPN2 | |
| SCHEMBL31455264 | 0.82 | USP30 (0.39) | JAK2JAK3 | |
| SCHEMBL31455205 | 0.82 | PRKCQ (0.38) | JAK2JAK3PTK2JAK1 | |
| SCHEMBL31455277 | 0.79 | PRKCQ (0.37) | SLC34A1 | |
| SCHEMBL31455508 | 0.78 | MEN1 (0.39) | JAK3SLC34A1LCKBTK | |
| SCHEMBL31455299 | 0.77 | SLC34A1 (0.40) | JAK2JAK3PTK2SLC34A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |