Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 5/20 | 0.38 |
| ▸ | JAK2 | O60674 | 4/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455508 | 0.88 | MEN1 (0.39) | SLC34A1NAMPTJAK3IGF1RLCK | |
| SCHEMBL31455018 | 0.86 | SLC34A1 (0.42) | SLC34A1NAMPTJAK3JAK2PTK2 | |
| SCHEMBL31420326 | 0.85 | NAMPT (0.40) | NAMPTJAK3JAK2PTK2LCK | |
| SCHEMBL31455504 | 0.80 | MKNK1 (0.40) | NAMPTJAK3JAK2PTK2IGF1R | |
| SCHEMBL31455102 | 0.79 | NAMPT (0.45) | NAMPTJAK3JAK2PTK2IGF1R | |
| SCHEMBL31455378 | 0.79 | HPGDS (0.44) | NAMPTJAK3JAK2PTK2LCK | |
| SCHEMBL31455277 | 0.79 | PRKCQ (0.37) | SLC34A1NAMPTPRKCQUSP30TP53 | |
| SCHEMBL31454988 | 0.78 | MAPK1 (0.43) | SLC34A1JAK3LCKBTK | |
| SCHEMBL31420375 | 0.77 | NAMPT (0.51) | NAMPTJAK3JAK2PTK2IGF1R | |
| SCHEMBL31455683 | 0.77 | JAK2 (0.46) | SLC34A1JAK3JAK2PTK2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |