Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455299 | 0.88 | SLC34A1 (0.40) | IGF1RSLC34A1JAK3LCKBTK | |
| SCHEMBL31455504 | 0.83 | MKNK1 (0.40) | MEN1KMT2AIGF1RMAPTALDH1A1 | |
| SCHEMBL31454988 | 0.81 | MAPK1 (0.43) | SLC34A1MAPTJAK3LCKBTK | |
| SCHEMBL31420326 | 0.80 | NAMPT (0.40) | JAK3LCKBTKGPR119NAMPT | |
| SCHEMBL31455683 | 0.78 | JAK2 (0.46) | SLC34A1JAK3LCKBTK | |
| SCHEMBL19175230 | 0.76 | LMNA (0.44) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL31455485 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL31455266 | 0.76 | USP30 (0.41) | IGF1RSLC34A1MAPTALDH1A1MKNK1 | |
| SCHEMBL31455102 | 0.74 | NAMPT (0.45) | IGF1RJAK3LCKBTKGPR119 | |
| SCHEMBL31455018 | 0.73 | SLC34A1 (0.42) | IGF1RSLC34A1JAK3LCKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |