Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455642 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TRPV1TDP1MAPTKMT2A | |
| SCHEMBL31455362 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TRPV1TDP1MAPTKMT2A | |
| SCHEMBL31455366 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TRPV1TDP1MAPTKMT2A | |
| SCHEMBL31455312 | 0.82 | LTA4H (0.45) | — | |
| SCHEMBL31455623 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TRPV1TDP1MAPTKMT2A | |
| SCHEMBL31455394 | 0.80 | MAPT (0.36) | ALDH1A1TDP1MAPTHPGDHSD17B10 | |
| SCHEMBL31455425 | 0.79 | GSK3B (0.36) | ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31455361 | 0.78 | ADORA1 (0.40) | MAPTKMT2AHTTLMNAMEN1 | |
| SCHEMBL25384573 | 0.76 | ABCG2 (0.54) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL31454989 | 0.76 | ABCG2 (0.54) | ALDH1A1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |