Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455342 | 0.89 | ALDH1A1 (0.57) | ALDH1A1MAPTTDP1TRPV1MEN1 | |
| SCHEMBL31455017 | 0.87 | ALDH1A1 (0.48) | ALDH1A1TDP1TRPV1OPRM1MEN1 | |
| SCHEMBL31455642 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTTDP1TRPV1MEN1 | |
| SCHEMBL31455545 | 0.78 | ABCG2 (0.41) | MAPTMEN1KMT2ASMN1; SMN2ABCG2 | |
| SCHEMBL31455361 | 0.78 | ADORA1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL31455449 | 0.76 | GSK3B (0.39) | ALDH1A1MAPTTDP1SMN1; SMN2NPC1 | |
| SCHEMBL31455312 | 0.76 | LTA4H (0.45) | ABCG2 | |
| SCHEMBL31455719 | 0.75 | ABCG2 (0.45) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31455366 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTTDP1TRPV1MEN1 | |
| SCHEMBL31455427 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTOPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |