Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455366 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HDAC1HDAC2TDP1MEN1 | |
| SCHEMBL31455362 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31455623 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HDAC1HDAC2TDP1MEN1 | |
| SCHEMBL31455427 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL31455275 | 0.76 | BRD9 (0.43) | HDAC1HDAC2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31455364 | 0.75 | ADORA1 (0.42) | HDAC1HDAC2MEN1KMT2ANPC1 | |
| SCHEMBL31455342 | 0.75 | ALDH1A1 (0.57) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31455694 | 0.74 | HDAC1 (0.46) | ALDH1A1HDAC1HDAC2TDP1SMN1; SMN2 | |
| SCHEMBL31455411 | 0.74 | HDAC1 (0.46) | ALDH1A1HDAC1HDAC2TDP1SMN1; SMN2 | |
| SCHEMBL31455225 | 0.74 | NPC1 (0.44) | ALDH1A1HDAC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |