Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461727 | 0.85 | TSHR (0.42) | KDM4EMAPTMEN1KMT2AGAA | |
| SCHEMBL31461679 | 0.79 | KDM4E (0.36) | KDM4EMAPTMEN1KMT2AGAA | |
| SCHEMBL11474094 | 0.73 | ALOX15 (0.46) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL370069 | 0.71 | PDE10A (0.43) | KDM4EMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL18304786 | 0.71 | ADORA2A (0.53) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL18304738 | 0.71 | ADORA2A (0.53) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL31461658 | 0.70 | ADORA3 (0.61) | MEN1KMT2AGAALMNAPDE10A | |
| SCHEMBL16841278 | 0.70 | ADORA2A (0.73) | KDM4EMAPTGAAHSD17B10LMNA | |
| SCHEMBL362986 | 0.68 | HTR3E (0.56) | KDM4EMAPTMEN1KMT2AGAA | |
| SCHEMBL29974558 | 0.65 | ADORA2A (0.50) | KDM4EMEN1KMT2AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |