Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461727 | 0.79 | TSHR (0.42) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL31461670 | 0.79 | KDM4E (0.42) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL16280692 | 0.68 | ALDH1A1 (0.46) | KDM4EMAPTTP53POLBHSD17B10 | |
| SCHEMBL11474094 | 0.68 | ALOX15 (0.46) | KDM4EMAPTLMNATP53POLB | |
| SCHEMBL370069 | 0.66 | PDE10A (0.43) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL28363563 | 0.66 | KMT2A (0.41) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL31461658 | 0.65 | ADORA3 (0.61) | LMNAPDE10AMEN1KMT2AGAA | |
| SCHEMBL15522679 | 0.65 | KMT2A (0.53) | KDM4EPOLBHSD17B10KMT2AGAA | |
| SCHEMBL15692617 | 0.64 | KDM4E (0.39) | KDM4EMAPTPOLBHTTMEN1 | |
| SCHEMBL16841278 | 0.64 | ADORA2A (0.73) | KDM4EMAPTLMNATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |