SCHEMBL3146937

SCHEMBL3146937

FC(F)(F)c1cnc(-c2ccccc2)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 2/20 0.43
CYP11B1 P15538 1/20 0.43
ADORA2A P29274 2/20 0.43
TDP1 Q9NUW8 2/20 0.40
NR1H2 P55055 2/20 0.40
NR1H3 Q13133 2/20 0.40
KDM4E B2RXH2 2/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
BACE1 P56817 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
ALDH1A1 P00352 2/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
ULK1 O75385 1/20 0.37
ADORA1 P30542 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13327603 0.82 AR (0.43) TDP1NR1H2NR1H3RAB9ASMN1; SMN2
SCHEMBL3147240 0.81 TDO2 (0.44) ADORA2ANR1H2NR1H3KDM4ERAB9A
SCHEMBL10300877 0.74 ADORA2A (0.50) CYP11B2CYP11B1ADORA2AKDM4ERAB9A
SCHEMBL4154540 0.74 CYP11B1 (0.50) CYP11B2CYP11B1ADORA2ATDP1KDM4E
SCHEMBL12337987 0.73 SSTR4 (0.42) NR1H2NR1H3RAB9ABACE1ALDH1A1
SCHEMBL26092182 0.73 ULK1 (0.39) CYP11B2CYP11B1NR1H2NR1H3SMN1; SMN2
SCHEMBL3147045 0.73 PIK3CD (0.40) CYP11B2CYP11B1NR1H2NR1H3BACE1
SCHEMBL25428909 0.71 MAPT (0.50) TDP1ALDH1A1NPSR1
SCHEMBL2404786 0.71 ADORA2A (0.44) CYP11B2ADORA2ATDP1KDM4ERAB9A
SCHEMBL1334325 0.71 ADORA1 (0.58) ADORA2AADORA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1348711-B1 LUMINESCENT ELEMENT AND DISPLAY CANON KK (JP) 2018-06-13 EP disclosed
EP-1889891-B1 Luminescence device and display apparatus CANON KK (JP) 2017-11-22 EP disclosed
US-20150076478-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2015-03-19 US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
US-7687155-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2010-03-30 US disclosed
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-07-23 US disclosed
US-7544426-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2009-06-09 US disclosed
US-7527879-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
CN-100375749-C Luminescence device and display apparatus CANON KK (JP) 2008-03-19 CN disclosed
EP-1889891-A2 Luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2008-02-20 EP disclosed
EP-1881050-A2 Luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2008-01-23 EP disclosed
US-20070216294-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-09-20 US disclosed
US-20070212570-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2007-09-13 US disclosed
US-7147935-B2 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2006-12-12 US disclosed
CN-1285601-C Light emitting device and display CANON KK (JP) 2006-11-22 CN disclosed
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2006-08-10 US disclosed
CN-1781925-A Luminescence device and display apparatus CANON KK (JP) 2006-06-07 CN disclosed
CN-1474826-A Light emitting device and display ������������ʽ���� 2004-02-11 CN disclosed
EP-1348711-A1 LUMINESCENT ELEMENT AND DISPLAY CANON KABUSHIKI KAISHA (JP) 2003-10-01 EP disclosed
US-20030068526-A1 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060177694-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency AP3M1, MLEC, MLX CYP11B2 3389/4885CYP11B1 3892/4885ADORA2A 4502/4885
US-20090184634-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS SOD1, NLRP1, LUC7L2 CYP11B2 3728/4885CYP11B1 3868/4885ADORA2A 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.