Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | MME | P08473 | 4/20 | 0.48 |
| ▸ | PCNA | P12004 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147877 | 0.88 | NAALAD2 (0.61) | FOLH1NAALAD2ACEMMECPA1 | |
| SCHEMBL4147882 | 0.88 | NAALAD2 (0.61) | FOLH1NAALAD2ACEMMECPA1 | |
| SCHEMBL13123764 | 0.85 | ALDH1A1 (0.48) | PCNA | |
| SCHEMBL31072235 | 0.85 | ALDH1A1 (0.48) | PCNA | |
| SCHEMBL30081063 | 0.84 | ACE (0.56) | FOLH1NAALAD2ACEMMECPA1 | |
| SCHEMBL30081065 | 0.84 | ACE (0.56) | FOLH1NAALAD2ACEMMECPA1 | |
| SCHEMBL4147927 | 0.84 | ITGB3 (0.62) | FOLH1NAALAD2ACEMMEITGB3 | |
| SCHEMBL4147924 | 0.84 | ITGB3 (0.62) | FOLH1NAALAD2ACEMMEITGB3 | |
| SCHEMBL4147417 | 0.84 | ITGB3 (0.62) | FOLH1NAALAD2ACEMMEITGB3 | |
| SCHEMBL4147413 | 0.84 | ITGB3 (0.62) | FOLH1NAALAD2ACEMMEITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10888361-B2 | Devices, compositions and methods for bone and tissue augmentation | REVA Medical LLC (US) | 2021-01-12 | — | — | US | disclosed |
| US-20190117281-A1 | DEVICES, COMPOSITIONS AND METHODS FOR BONE AND TISSUE AUGMENTATION | REVA MEDICAL, LLC | 2019-04-25 | — | — | US | disclosed |
| US-9782523-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2017-10-10 | — | — | US | disclosed |
| EP-2446907-A1 | Side-chain crystallizable polymers for medical applications | Reva Medical, Inc. (US) | 2012-05-02 | — | — | EP | disclosed |
| US-8133959-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-8124700-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110213456-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | REVA MEDICAL, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213090-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | REVA MEDICAL, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110212050-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | REVA MEDICAL, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7939611-B2 | Side-chain crystallizable polymers for medical applications | REVA MEDICAL, INC. (US) | 2011-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10888361-B2 | Devices, compositions and methods for bone and tissue augmentation | BMP2, COL2A1, MATR3 | FOLH1 2389/4885NAALAD2 3165/4885ACE 1668/4885 |
| US-20110212050-A1 | SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS | IRS1, INSRR, LCP1 | FOLH1 2176/4885NAALAD2 4213/4885ACE 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.