Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 4/20 | 0.34 |
| ▸ | RXRG | P48443 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474074 | 0.85 | DGAT1 (0.38) | RXRARARBRARGRARAKDM4E | |
| SCHEMBL31474036 | 0.81 | SYK (0.35) | RXRARARBRARGRARAKDM4E | |
| SCHEMBL5872835 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1MEN1KMT2AASPH | |
| SCHEMBL30353241 | 0.70 | PKM (0.40) | RXRARARBRARGRARAKDM4E | |
| SCHEMBL1713733 | 0.69 | KDM4E (0.54) | KDM4EALDH1A1MEN1KMT2AASPH | |
| SCHEMBL31474238 | 0.68 | RXRA (0.43) | RXRARARBRARGRARARXRB | |
| SCHEMBL18650553 | 0.67 | RXRA (0.56) | RXRARARBRARGRARAKDM4E | |
| SCHEMBL9731273 | 0.66 | RXRA (0.39) | RXRARARBRARGRARAKDM4E | |
| SCHEMBL31474080 | 0.66 | RXRA (0.42) | RXRARARBRARGRARAALDH1A1 | |
| SCHEMBL16992626 | 0.66 | CA9 (0.42) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |