Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474080 | 0.85 | RXRA (0.42) | SYKPKMALDH1A1HPGDTSHR | |
| SCHEMBL31474013 | 0.81 | RXRA (0.39) | SYKALDH1A1HPGDHSD17B10RARB | |
| SCHEMBL31474074 | 0.80 | DGAT1 (0.38) | ALDH1A1RARBRARGRXRARARA | |
| SCHEMBL883735 | 0.74 | RAB9A (0.42) | PKMALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL31474057 | 0.74 | PKM (0.36) | SYKPKMALDH1A1HPGDTSHR | |
| SCHEMBL31474132 | 0.74 | KDM4E (0.41) | PKMALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL522786 | 0.73 | CA12 (0.47) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL31474127 | 0.71 | PDK2 (0.35) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL17276295 | 0.70 | RARG (0.42) | PKMALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL24570280 | 0.70 | KDM4E (0.38) | PKMALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120081791-A | Heteroaryl compounds, process for their preparation and their use in medicine | 江苏恒瑞医药股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |