Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430125 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EGAAALOX12 | |
| SCHEMBL31476392 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EALOX12HSD17B10 | |
| SCHEMBL31476442 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23198963 | 0.72 | AR (0.42) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL20390458 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EGAAALOX12 | |
| SCHEMBL8408204 | 0.70 | ACHE (0.52) | ALDH1A1MAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL10092666 | 0.69 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EGAAALOX12 | |
| SCHEMBL7793706 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EGAAALOX12 | |
| SCHEMBL1934004 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EGAAALOX12 | |
| SCHEMBL29430132 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EGAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | PFAS, FLI1, ARFGEF1 | ALDH1A1 1109/4885MAPT 1822/4885KDM4E 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.