Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31476875 | 0.86 | WDR5 (0.38) | ALDH1A1KMT2APTK2BKDM4EWDR5 | |
| SCHEMBL27354577 | 0.81 | PPARA (0.37) | ALDH1A1KMT2APTK2BKDM4EPTPN11 | |
| SCHEMBL31476885 | 0.80 | CD274 (0.39) | CD274 | |
| SCHEMBL27354578 | 0.76 | PPARA (0.36) | ALDH1A1KMT2APTK2BKDM4EPTPN11 | |
| SCHEMBL956632 | 0.65 | SLC22A12 (0.78) | ALDH1A1SLC22A12 | |
| SCHEMBL27355404 | 0.64 | CXCL12 (0.38) | ALDH1A1KDM4ECYP4F2CYP4A11 | |
| SCHEMBL10699791 | 0.64 | ALDH1A1 (0.56) | ALDH1A1KMT2APTK2BKDM4ETTR | |
| SCHEMBL27355402 | 0.61 | EGFR (0.44) | KDM4E | |
| SCHEMBL31409462 | 0.61 | GAA (0.68) | ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL1096998 | 0.61 | GAA (0.68) | ALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119730847-A | NRF2 protein degradation agent | 盖尼米德肿瘤学股份有限公司 | 2025-03-28 | — | — | CN | disclosed |