Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 10/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422555 | 0.87 | PTGS2 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27480602 | 0.79 | RXRA (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30353435 | 0.79 | RXRA (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2183673 | 0.78 | CTSK (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2183876 | 0.74 | PSEN1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3433216 | 0.72 | PSEN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4266768 | 0.71 | KEAP1 (0.51) | APP | |
| SCHEMBL27705864 | 0.71 | KEAP1 (0.51) | APP | |
| SCHEMBL27705669 | 0.71 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4260357 | 0.71 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |