SCHEMBL31483022

SCHEMBL31483022

Cn1cc(OCCN)cn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
LTA4H P09960 2/20 0.36
PLA2G2A P14555 1/20 0.36
FGFR1 P11362 2/20 0.36
FGFR2 P21802 1/20 0.36
FGFR3 P22607 1/20 0.36
LRRK2 Q5S007 1/20 0.36
AKT1 P31749 3/20 0.34
DYRK3 O43781 2/20 0.34
ROCK2 O75116 2/20 0.34
RPS6KA5 O75582 2/20 0.34
PRKD3 O94806 2/20 0.34
MAP4K4 O95819 2/20 0.34
PIM1 P11309 2/20 0.34
PHKG2 P15735 2/20 0.34
PRKACA P17612 2/20 0.34
CLK2 P49760 2/20 0.34
PRKX P51817 2/20 0.34
PRKCD Q05655 2/20 0.34
PRKG2 Q13237 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24866429 0.84 LTA4H (0.39) LTA4HSMN1; SMN2
SCHEMBL30954555 0.78 CHRNB2 (0.47) FGFR1FGFR2FGFR3ROCK2MAP4K4
SCHEMBL21888512 0.78
SCHEMBL12671453 0.75 LOXL2 (0.42) FGFR1FGFR2FGFR3LRRK2AURKB
SCHEMBL31483016 0.74 ALDH1A1 (0.40) SMN1; SMN2MKNK2MAPK1
SCHEMBL31605739 0.74 KMT2A (0.47) FGFR1FGFR2FGFR3SMN1; SMN2
SCHEMBL22723808 0.73 PDK2 (0.45) FGFR1FGFR2FGFR3MAP4K4SMN1; SMN2
SCHEMBL30561620 0.72 ERN1 (0.33) FGFR1FGFR2FGFR3LRRK2MAP4K4
SCHEMBL31358628 0.72 DUT (0.41)
SCHEMBL8843834 0.70 LRRK2 (0.34) FGFR1FGFR2FGFR3LRRK2MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841829-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2025-04-18 CN disclosed