Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954555 | 0.78 | CHRNB2 (0.47) | ALDH1A1HTTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL22723808 | 0.76 | PDK2 (0.45) | ALDH1A1HTTSMN1; SMN2L3MBTL1PDK2 | |
| SCHEMBL31483022 | 0.74 | TAAR1 (0.41) | SMN1; SMN2MAPK1MKNK2 | |
| SCHEMBL30600853 | 0.74 | NPC1 (0.46) | ALDH1A1HTTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL24866429 | 0.73 | LTA4H (0.39) | ALDH1A1HTTSMN1; SMN2L3MBTL1PDK2 | |
| SCHEMBL31483076 | 0.72 | SMN1; SMN2 (0.44) | ALDH1A1HTTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL3260918 | 0.71 | MKNK1 (0.42) | ALDH1A1HTTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL31483063 | 0.70 | MTNR1A (0.47) | ALDH1A1SMN1; SMN2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL21246174 | 0.70 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2L3MBTL1HSD17B10MEN1 | |
| SCHEMBL31483087 | 0.70 | MTNR1A (0.73) | ALDH1A1SMN1; SMN2MTNR1AMTNR1BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |