Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496913 | 0.97 | MAOA (0.35) | OPRK1KMT2AMAOAMAOBKDM4E | |
| SCHEMBL31496960 | 0.82 | HCRTR1 (0.32) | OPRK1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL31496984 | 0.82 | KMT2A (0.33) | KMT2AALOX15KDM4E | |
| SCHEMBL31496873 | 0.81 | ALDH1A1 (0.32) | MAOAMAOBHCRTR1HCRTR2 | |
| SCHEMBL31261072 | 0.80 | KMT2A (0.36) | KMT2AALOX15KDM4E | |
| SCHEMBL31496993 | 0.80 | KDM4E (0.37) | KMT2AALOX15KDM4ETP53 | |
| SCHEMBL31388128 | 0.79 | KDM4E (0.36) | KMT2AALOX15KDM4E | |
| SCHEMBL31496920 | 0.78 | KMT2A (0.32) | OPRK1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL31496970 | 0.77 | LMNA (0.31) | KMT2AMAOAMAOBHCRTR1HCRTR2 | |
| SCHEMBL30752934 | 0.76 | KMT2A (0.34) | KMT2AALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |