Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.31 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496960 | 0.95 | HCRTR1 (0.32) | HCRTR1HCRTR2OPRK1L3MBTL1 | |
| SCHEMBL31496970 | 0.87 | LMNA (0.31) | KMT2AHCRTR1HCRTR2SCN9ASCN5A | |
| SCHEMBL31496913 | 0.82 | MAOA (0.35) | KMT2AHCRTR1HCRTR2OPRK1SCN9A | |
| SCHEMBL31496873 | 0.82 | ALDH1A1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL30753090 | 0.82 | THRA (0.32) | KMT2ATHRATHRB | |
| SCHEMBL31496937 | 0.78 | OPRK1 (0.33) | KMT2AHCRTR1HCRTR2OPRK1 | |
| SCHEMBL31496911 | 0.77 | RAB9A (0.32) | L3MBTL1 | |
| SCHEMBL31496829 | 0.76 | PARP10 (0.36) | THRATHRBPDE4APDE4BPDE4C | |
| SCHEMBL31496862 | 0.71 | KCNH2 (0.34) | — | |
| SCHEMBL31388158 | 0.66 | AAK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |