Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140520 | 0.91 | LMNA (0.42) | TBXA2RLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2100541 | 0.82 | KDM4E (0.55) | TBXA2RPPARGLMNAKDM4EAGTR1 | |
| SCHEMBL16456515 | 0.75 | ALDH1A1 (0.57) | TBXA2RALOX5APLMNAKDM4ECYP1A2 | |
| SCHEMBL2097508 | 0.75 | TP53 (0.53) | TBXA2RLMNAAGTR1AGTR2POLB | |
| SCHEMBL1852575 | 0.74 | MAPT (0.48) | TBXA2RLMNAKDM4ECYP3A4CYP2C9 | |
| SCHEMBL3149955 | 0.74 | DPP4 (0.47) | — | |
| SCHEMBL2161533 | 0.70 | KDM4E (0.68) | PPARGLMNAKDM4EALDH1A1GAA | |
| SCHEMBL7436459 | 0.70 | TBXA2R (0.52) | TBXA2RLMNAALDH1A1AGTR1AGTR2 | |
| SCHEMBL6528718 | 0.70 | L3MBTL1 (0.46) | LMNAKDM4ETSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3718063 | 0.70 | RAB9A (0.67) | TBXA2RALOX5APLMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863790-B1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | SANOFI AVENTIS (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-1863790-A1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | Sanofi-Aventis (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099943-A1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2006-09-28 | — | — | WO | disclosed |