Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31509575 | 0.90 | PSMB1 (0.47) | LTA4HMDM2PTPN1HDAC8 | |
| SCHEMBL31509543 | 0.81 | RAB9A (0.49) | LTA4HKMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30705439 | 0.80 | KMT2A (0.53) | EPHX2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15691997 | 0.79 | NAMPT (0.49) | MDM2EPHX2KMT2AHDAC1 | |
| SCHEMBL31509474 | 0.78 | LTA4H (0.51) | LTA4HKMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27810168 | 0.78 | EPHX2 (0.60) | MDM2EPHX2KMT2A | |
| SCHEMBL7395807 | 0.76 | CA12 (0.49) | MDM2EPHX2KMT2A | |
| SCHEMBL26352259 | 0.75 | KMT2A (0.51) | EPHX2KMT2A | |
| SCHEMBL27072523 | 0.75 | KMT2A (0.51) | EPHX2KMT2A | |
| SCHEMBL29529271 | 0.75 | PABPC1 (0.48) | MDM2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085489-A1 | GSPT1-DEGRADING COMPOUNDS, ANTI-CD33 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-24 | — | — | WO | disclosed |