SCHEMBL31512663

SCHEMBL31512663

NCc1ccc2c(c1)Oc1cccc(Cl)c1N2

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PNMT P11086 2/20 0.38
▸ CSNK2A1 P68400 5/20 0.36
▸ ALOX5 P09917 3/20 0.35
▸ AHR P35869 2/20 0.35
▸ TAAR1 Q96RJ0 1/20 0.34
▸ CSNK2A2 P19784 1/20 0.32
▸ CSNK2B P67870 1/20 0.32
▸ CSNK2A3 Q8NEV1 1/20 0.32
▸ MRGPRX4 Q96LA9 1/20 0.31
▸ ENPP2 Q13822 1/20 0.31
▸ HTR2B P41595 1/20 0.31
▸ KLKB1 P03952 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31512579 0.77 PNMT (0.43) PNMTCSNK2A1ALOX5AHRTAAR1
SCHEMBL2724592 0.76 ALOX5 (0.59) ALOX5AHR
Hydrochloric Acid SCHEMBL7593760 0.75 ALOX5 (0.57) ALOX5AHRHTR2B
Ammonia Solution, Strong SCHEMBL27849239 0.75 ALOX5 (0.57) ALOX5AHR
SCHEMBL31512624 0.74 ALDH1A1 (0.39) ALOX5AHR
SCHEMBL31512617 0.71 MEN1 (0.37) ALOX5AHRHTR2B
SCHEMBL31512597 0.71 MITF (0.39) ALOX5TAAR1
SCHEMBL6265360 0.69 ALOX5 (0.57) ALOX5
SCHEMBL31558291 0.68 AHR (0.50) ALOX5AHR
SCHEMBL31512592 0.68 TAAR1 (0.42) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326726-A1 FERROPTOSIS INHIBITORS-PHENOXAZINE ACETAMIDES SIRONAX BEIJING CO LTD (CN) 2025-10-23 — — US disclosed
CN-119866332-A Iron death inhibitor-phenoxazine acetamides 维泰瑞隆(北京)生物科技有限公司 2025-04-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326726-A1 FERROPTOSIS INHIBITORS-PHENOXAZINE ACETAMIDES AIFM2, GPX4, FECH PNMT 2663/4885CSNK2A1 3799/4885ALOX5 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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