Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 3/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107340 | 0.90 | — | — | |
| SCHEMBL8298097 | 0.81 | HRH3 (0.40) | HRH3CHRM1CHRM2HTR1AADRA2A | |
| SCHEMBL8266529 | 0.77 | HRH3 (0.38) | HRH3CHRM1CHRM2HTR1AADRA2A | |
| SCHEMBL25082408 | 0.76 | GNAI3 (0.38) | HRH3CHRM1CHRM2HTR1AADRA2A | |
| SCHEMBL8224168 | 0.75 | — | — | |
| SCHEMBL3436804 | 0.75 | — | — | |
| SCHEMBL8298892 | 0.75 | SMN1; SMN2 (0.39) | HRH3CHRM1CHRM2HTR1AADRA2A | |
| SCHEMBL254092 | 0.75 | — | — | |
| SCHEMBL29178515 | 0.74 | LTA4H (0.31) | — | |
| SCHEMBL9959055 | 0.74 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867650-B1 | HYDROXYMETHYLBORON COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |
| US-7696347-B2 | Oxymethyl boron compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-13 | — | — | US | claimed |
| US-20080242859-A1 | Oxymethyl Boron Compounds | EISAI R&D MANAGEMENT CO., LTD (JP) | 2008-10-02 | — | — | US | claimed |
| EP-1867650-A1 | HYDROXYMETHYLBORON COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2007-12-19 | — | — | EP | claimed |
| EP-4323363-A1 | NEW PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-02-21 | — | — | EP | disclosed |
| US-20230023140-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-01-26 | — | — | US | disclosed |
| EP-4050006-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK Biopharmaceuticals Co., Ltd. (KR) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021080359-A1 | BICYCLIC COMPOUND AND USE THEREOF | 에스케이바이오팜 주식회사 | 2021-04-29 | — | — | WO | disclosed |
| EP-2953681-B1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2017-03-15 | — | — | EP | disclosed |
| EP-2953681-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | Boehringer Ingelheim International GmbH (DE) | 2015-12-16 | — | — | EP | disclosed |
| US-8927531-B2 | Indanyloxydihydrobenzofuranylacetic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-06 | — | — | US | disclosed |
| WO-2014122067-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-14 | — | — | WO | disclosed |
| US-20140221349-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-07 | — | — | US | disclosed |
| EP-1867650-B1 | HYDROXYMETHYLBORON COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-7696347-B2 | Oxymethyl boron compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20080242859-A1 | Oxymethyl Boron Compounds | EISAI R&D MANAGEMENT CO., LTD (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1867650-A1 | HYDROXYMETHYLBORON COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230023140-A1 | BICYCLIC COMPOUND AND USE THEREOF | PRMT5, PRMT6, PRMT1 | HRH3 1633/4885CHRM1 2570/4885CHRM2 3151/4885 |
| US-20080242859-A1 | Oxymethyl Boron Compounds | BPGM, DDT, DBN1 | HRH3 209/4885CHRM1 2006/4885CHRM2 1393/4885 |
| US-20140221349-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | GPR119, GPBAR1, GPR52 | HRH3 1564/4885CHRM1 111/4885CHRM2 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.