Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567101 | 0.85 | MTNR1B (0.63) | MTNR1BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL18666151 | 0.85 | MTNR1B (0.63) | MTNR1BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL18666149 | 0.83 | ALDH1A1 (0.55) | MTNR1BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL18666146 | 0.79 | ADRA2C (0.54) | MTNR1BALDH1A1LMNAPOLBTDP1 | |
| SCHEMBL29660113 | 0.79 | ADRA2C (0.54) | MTNR1BALDH1A1LMNAPOLBTDP1 | |
| SCHEMBL31522175 | 0.78 | MTNR1B (0.56) | MTNR1BKDM4EALDH1A1POLBPDGFRA | |
| SCHEMBL31120712 | 0.78 | MTNR1B (0.53) | MTNR1BKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL18666150 | 0.77 | MTNR1B (0.47) | MTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL25386731 | 0.77 | MTNR1B (0.61) | MTNR1BALDH1A1LMNAPOLBPKM | |
| SCHEMBL31522180 | 0.77 | MTNR1B (0.50) | MTNR1BKDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |