Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.68 |
| ▸ | CETP | P11597 | 1/20 | 0.68 |
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | AXL | P30530 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.56 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | NEK2 | P51955 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.51 |
| ▸ | ACLY | P53396 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441248 | 0.82 | PTPN1 (0.71) | PTPN1PTGS2CETPIGF1RSRC | |
| Avarol SCHEMBL31517137 | 0.81 | PTPN1 (1.00) | PTPN1PTGS2CETPIGF1RSRC | |
| Avarol SCHEMBL21397196 | 0.81 | PTPN1 (1.00) | PTPN1PTGS2CETPIGF1RSRC | |
| Avarol SCHEMBL186460 | 0.81 | PTPN1 (1.00) | PTPN1PTGS2CETPIGF1RSRC | |
| Avarol SCHEMBL10402772 | 0.81 | PTPN1 (1.00) | PTPN1PTGS2CETPIGF1RSRC | |
| Avarol SCHEMBL9477102 | 0.80 | PTPN1 (0.98) | PTPN1PTGS2CETPIGF1RSRC | |
| Avarol SCHEMBL9477704 | 0.78 | PTPN1 (0.94) | PTPN1PTGS2CETPIGF1RSRC | |
| SCHEMBL3680453 | 0.78 | PTGS2 (0.63) | PTPN1PTGS2CETPIGF1RSRC | |
| SCHEMBL31536047 | 0.75 | PTPN1 (1.00) | PTPN1PTGS2CETPIGF1RSRC | |
| Avarol SCHEMBL9478364 | 0.72 | PTPN1 (0.80) | PTPN1PTGS2CETPIGF1RSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122146-A1 | COMPOUNDS FOR REDUCING NEUROINFLAMMATION | THE SCRIPPS RESEARCH INSTITUTE | 2025-04-17 | — | — | US | claimed |
| US-20250122146-A1 | COMPOUNDS FOR REDUCING NEUROINFLAMMATION | THE SCRIPPS RESEARCH INSTITUTE | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122146-A1 | COMPOUNDS FOR REDUCING NEUROINFLAMMATION | HSF1, HSPA2, KEAP1 | PTPN1 3982/4885PTGS2 267/4885CETP 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.