Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637306 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BALDH1A1KDM4ETAAR1 | |
| SCHEMBL3503975 | 0.82 | FFAR1 (0.67) | HRH1FFAR1FFAR4RIPK1SLC6A2 | |
| SCHEMBL5105916 | 0.80 | HRH1 (0.51) | HRH1FFAR1FFAR4RIPK1SLC6A2 | |
| SCHEMBL8496411 | 0.80 | HRH1 (0.57) | HRH1RIPK1SLC6A2SLC6A4LTA4H | |
| SCHEMBL3809518 | 0.78 | FFAR1 (0.58) | HRH1FFAR1FFAR4RIPK1SLC6A2 | |
| SCHEMBL8493643 | 0.77 | RECQL (0.55) | HRH1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL17040296 | 0.77 | CYP2D6 (0.52) | HRH1RIPK1SLC6A2SLC6A4MTNR1A | |
| SCHEMBL24018828 | 0.76 | HRH1 (0.61) | HRH1RIPK1SLC6A2SLC6A4TAAR1 | |
| SCHEMBL2595163 | 0.76 | MPO (0.62) | SLC6A4KDM4ETAAR1 | |
| SCHEMBL8495825 | 0.76 | HRH1 (0.61) | HRH1FFAR1FFAR4RIPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281180-B2 | Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same | NEW YORK UNIVERSITY (US) | 2025-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281180-B2 | Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same | WNT1, WNT3, WNT3A | HRH1 2672/4885FFAR1 4283/4885FFAR4 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.