Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926773 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL28754175 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL3920170 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL3920174 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL7859393 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL6579051 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL6576494 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL6576487 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 | |
| SCHEMBL10799093 | 0.80 | TAAR1 (0.39) | ALDH1A1LMNASMN1; SMN2AOC3TDP1 | |
| SCHEMBL6493189 | 0.78 | TSHR (0.46) | ALDH1A1MAPTLMNASMN1; SMN2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665246-A | Method of producing ethynyl aromatic compounds | CHEM BIOCHEM RESEARCH, INC. (US) | 1987-05-12 | — | — | US | claimed |
| CN-114560892-A | Chiral tridentate nitrogen phosphine ligand synthesized based on ferrocene skeleton and application thereof | 广东工业大学 | 2022-05-31 | — | — | CN | disclosed |
| US-8093256-B2 | Use of 8-substituted-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives | SANOFI-AVENTIS (FR) | 2012-01-10 | — | — | US | disclosed |
| EP-1608654-B1 | 8-SUBSTITUTED-6, 7, 8,9-TETRAHY9DROPYRIMIDO (1,2- a) PYRIMIDIN-4-ONE DERIVATIVES | SANOFI AVENTIS (FR) | 2009-12-23 | — | — | EP | disclosed |
| EP-1934159-B1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF SE (DE) | 2009-03-25 | — | — | EP | disclosed |
| US-20090030235-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF SE (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-1934159-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF SE (DE) | 2008-06-25 | — | — | EP | disclosed |
| US-20080021046-A1 | USE OF 8-SUBSTITUTED-6,7,8,9-TETRAHYDROPYRIMIDO[1,2-a] PYRIMIDIN-4-ONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2008-01-24 | — | — | US | disclosed |
| US-7247638-B2 | 8-Substituted-6,7,8,9-tetrahydropyrimido [1,2-a] pyrimidin-4-one derivatives. | SANOFI-AVENTIS (FR) | 2007-07-24 | — | — | US | disclosed |
| WO-2007036570-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-05 | — | — | WO | disclosed |
| US-5266485-A | Biosynthesis | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0415344-B1 | Resin composition and process for preparing it | MITSUBISHI PETROCHEMICAL CO (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0520146-A1 | Process for preparing a thermoplastic resin composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-12-30 | — | — | EP | disclosed |
| US-5159008-A | High viscosity polyphenylene ether, low viscosity polyphenylen ether, polyamide unsaturated polar compound, and mineral filles and-or glass fibers | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| US-5091473-A | Polyamide, polyphenylene ether, block polymer, unsaturated acid or anhydride dispension, hydrogenated impact strength, rigidity, heat resistance | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0454156-A2 | Thermoplastic resin composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-5001181-A | polyamide blends with dispersed particles of polyphenylene ether which contain dispersed filler particles; strength, flexibility, solvent resistance | MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0415344-A1 | Resin composition and process for preparing it | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0357065-A2 | Resin composition | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4665246-A | Method of producing ethynyl aromatic compounds | CHEM BIOCHEM RESEARCH, INC. (US) | 1987-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030235-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | ADH5, ADH1C, ADH1A | ALDH1A1 76/4885MAPT 3024/4885LMNA 3099/4885 |
| US-20080021046-A1 | USE OF 8-SUBSTITUTED-6,7,8,9-TETRAHYDROPYRIMIDO[1,2-a] PYRIMIDIN-4-ONE DERIVATIVES | GSK3B, GSK3A, PSEN1 | ALDH1A1 2682/4885MAPT 60/4885LMNA 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.