Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6546260 | 0.82 | CA1 (0.31) | CA2CA1DNM1BDKRB2 | |
| SCHEMBL31284200 | 0.76 | DNM1 (0.41) | CA2CA1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL26504465 | 0.76 | CA2 (0.38) | CA2CA1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL24073189 | 0.74 | ALDH1A1 (0.38) | CA2CA1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL15929840 | 0.71 | CA2 (0.38) | CA2CA1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL28105393 | 0.71 | CYP3A4 (0.35) | CA2CA1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL26257861 | 0.70 | CA2 (0.41) | CA2CA1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL13672319 | 0.69 | LMNA (0.33) | TSHR | |
| SCHEMBL10309515 | 0.69 | LMNA (0.33) | TSHR | |
| Hydrochloric Acid SCHEMBL4654926 | 0.69 | DNM1 (0.39) | CA2CA1ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833857-B1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5756588-A | CURABLE COMPOSITION COMPRISING FLUOROPOLYMER, AROMATIC POLYHYDROXY CROSSLINKING AGENT, ORGANO-ONIUM COMPOUND, MONOHYDROXYFUNCTIONAL PHENOL CAPABLE OF DELAYING POST-COMPOUNDING INITIATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-05-26 | — | — | US | claimed |
| EP-0833857-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1997000906-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-01-09 | — | — | WO | claimed |
| US-20250382448-A1 | ACRYLIC RUBBER, RUBBER COMPOSITION AND CROSSLINKED PRODUCT OF SAME | DENKA COMPANY LTD (JP) | 2025-12-18 | — | — | US | disclosed |
| EP-4071183-B1 | ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION AND CROSSLINKED PRODUCT OF SAME | DENKA COMPANY LTD (JP) | 2025-11-12 | — | — | EP | disclosed |
| WO-2025127076-A1 | RUBBER COMPOSITION, CROSSLINKED PRODUCT THEREOF, AND METHOD FOR PRODUCING ACRYLIC RUBBER | デンカ株式会社 | 2025-06-19 | — | — | WO | disclosed |
| CN-111511777-B | Peroxide-cured halogenated elastomers with silicon-containing surface layers | 3M创新有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2024004617-A1 | ACRYLIC RUBBER, RUBBER COMPOSITION AND CROSSLINKED PRODUCT OF SAME | デンカ株式会社 | 2024-01-04 | — | — | WO | disclosed |
| US-11597816-B2 | Peroxide-cured halogenated elastomers having a silicon-containing superficial layer | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-03-07 | — | — | US | disclosed |
| US-20230013290-A1 | ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION AND CROSSLINKED PRODUCT OF SAME | DENKA COMPANY LIMITED (JP) | 2023-01-19 | — | — | US | disclosed |
| US-20220389201-A1 | ACRYLIC RUBBER COMPOSITION AND CROSSLINKED PRODUCT THEREOF | DENKA COMPANY LIMITED (JP) | 2022-12-08 | — | — | US | disclosed |
| US-6310141-B1 | FLUOROELASTOMER COPOLYMERS | DYNEON LLC | 2001-10-30 | — | — | US | disclosed |
| US-6300446-B1 | Fluorine-containing copolymer and composition thereof | ASAHI GLASS COMPANY, LIMITED (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1101994-A2 | Fuel hose | Tokai Rubber Industries, Ltd. (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1090935-A1 | FLUOROCOPOLYMER AND COMPOSITION THEREOF | ASAHI GLASS COMPANY LTD. (JP) | 2001-04-11 | — | — | EP | disclosed |
| US-5756588-A | CURABLE COMPOSITION COMPRISING FLUOROPOLYMER, AROMATIC POLYHYDROXY CROSSLINKING AGENT, ORGANO-ONIUM COMPOUND, MONOHYDROXYFUNCTIONAL PHENOL CAPABLE OF DELAYING POST-COMPOUNDING INITIATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0833857-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000906-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-01-09 | — | — | WO | disclosed |
| US-5588469-A | HAVING INNERMOST AND OUTER VULCANIZATION LAYERS CONTAINING 1,8-DIAZABICYCLO/5.4.0/UNDEC-7-ENE SALTS AND ORGANOPHOSPHONIUM SALTS, FLEXIBLE FLUOROPOLYMER INNER LAYER | MARUGO RUBBER INDUSTRIES, LTD. (JP) | 1996-12-31 | — | — | US | disclosed |