Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608798 | 1.00 | P2RX7 (0.37) | P2RX7SCN9ASCN10AMRGPRX4TRPV4 | |
| SCHEMBL31292214 | 0.81 | DGAT1 (0.39) | P2RX7SCN9AMRGPRX4 | |
| SCHEMBL17583206 | 0.79 | POLB (0.37) | P2RX7 | |
| SCHEMBL30628308 | 0.77 | TRPV4 (0.35) | P2RX7MRGPRX4TRPV4 | |
| SCHEMBL160471 | 0.77 | TRPV4 (0.35) | P2RX7MRGPRX4TRPV4 | |
| SCHEMBL30628280 | 0.75 | RAB9A (0.42) | TRPV4 | |
| SCHEMBL17420645 | 0.75 | RAB9A (0.42) | TRPV4 | |
| SCHEMBL17420409 | 0.75 | L3MBTL1 (0.42) | — | |
| SCHEMBL3394893 | 0.75 | ALDH1A1 (0.48) | TRPV4 | |
| SCHEMBL17420522 | 0.75 | MRGPRX4 (0.40) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | disclosed |